cBioPortal offers countless ways to explore and interpret cancer genomics dataβ€”without needing to code. Below, we walk through a series of research questions using KRAS as an example gene to show how to use public datasets to uncover meaningful insights.

πŸ“ Note: These examples use the public cBioPortal instance but can be replicated on the Fred Hutch instance as well.

Example: Investigating KRAS in Cancer

Q1: How often is KRAS mutated in cancer?

oncoprint_kras_different_studies

KRAS_lollipop

KRAS_oncokb


Q2: Are KRAS mutations associated with clinical factors?

KRAS_clinical_covariates

KRAS_clinical_mut


Q3: Do KRAS mutations co-occur with other mutations?

KRAS_cooccurence


Q4: Do KRAS mutations affect survival?

KRAS_OS

KRAS_DFS


More Ways to Use cBioPortal


↩️ Back to: What is cBioPortal?